Ferguson had fielded strong side?s in The Red Devils? opening matches against Kaizer Chiefs and Orlando Pirates, with the likes of Wayne Rooney and Carlos Tevez featuring.
However, the 66-year old has opted to call upon the services of Rodrigo Possebon, Tom Cleverley and Craig Cathcart for the final of Vodacom Challenge game on Saturday.
The trio are regulars for United?s reserve side, with the latter duo also possessing senior squad numbers which suggests that they may feature for the full-team during the coming season.
Should the players impress, they could also be in line for a starting berth against Portsmouth in Nigeria on Sunday.
Possebon moved to England from Internacional, whom the Old Trafford outfit share a development link, in 2008 while Cathcart and Cleverley moved to Lancashire in 2005.
Liverpool Accept Pompey Crouch Bid - Report
The curtain-raiser: North against South
The curtain-raiser: North against South
Pompey Hit By Credit Crunch
Liverpool Accept Pompey Crouch Bid - Report